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Welcome to the KKGT, which stand for “Association for Quality Assessment in Therapeutic Drug Monitoring and Clinical Toxicology”. The objective of the association is to stimulate
the quality of Therapeutic Drug
Monitoring, Clinical Toxicology and
the analysis of other corporal-strange substances in laboratories. This includes
determination of serumlevels, pharmacokinetic calculations and simulations,
interpretation, together resulting
in a treatment advice to the physician. The
Association has Articles, an Executive and an office. Participants
to KKGT-EQAS will subscribe yearly to the programs and will then not influence
the composition of the Executive or the financial affairs of the Association. The Clinical Toxicology program is based on real
case histories. Drug spiked serum (lyophilised or liquid) or urine specimens (liquid)
are distributed with the case history (see example of a toxicology test). The
participants should perform analytical investigations and report the positive
and/or negative results: identities and concentrations of the drug/poison found
plus the methods of analysis used in addition. Interpretation of these lab data
and the advices for medical treatment belongs to this program. All individual results are collected in an
anonymized overall report to all participants. Comments on selected assay
methods and advices about treatment are added by the program coordinator
professor dr. D.R.A. Uges, or another hospital pharmacist-toxicologist. The Toxicology Program started in 1977, in the
Dutch language. From 2000- 2003 we had twice a year a proficiency-test with the UK-NEQAS. To download the form of test 2011.4 click right mousebutton and save as... For 2012 the costs for this program will be € 285 (19% VAT not included) To download general information about all programs and the participation form 2012 click right mousebutton and save as... DRUGS OF ABUSE PROGRAM: For 2012 the costs will be € 285 (19% VAT not included) Survey of all tested components from 1994-up to the present with links to the reports To download the form of test 2011.4A click right mousebutton and save as... To download the form of test 2011.4B click right mousebutton and save as...
INTERNATIONAL INTERLABORATORY CONTROL PROGRAM The
objectives of the program are to define sources of error in bioanalytical
methods, to contribute to the optimisation of the bioanalysis of antiretroviral
drugs and to establish interconvertibility of results among laboratories and
methods. In the past years plasma samples have been sent, spiked with known
amounts of antiretroviral drugs. The plasma has been obtained from HIV-negative
healthy volunteers. Participating laboratories are asked to measure the
concentration of the antiretroviral drugs and to report the results before the
indicated date. Results will be interpreted and reported back to participants. Please click here to read more about the organisation of this program. To see a (statistic) report example click here In
June 2003 we started round
5. This case included both measuring concentrations of antiretrovitral and a
clinical case. In
2012 To download the form of the first round 2011 click right mousebutton and save as... To download the form of the second round 2011 click right mousebutton and save as... To see the concentrations of 2011 click right mousebutton and save as...
After
a first free round of the International Interlaboratory Quality Control Program
for Therapeutic Drug Monitoring of Antifungal drugs we now invite you to
participate in the first and second round of this program. These rounds are
organised by the Dutch Association for Quality Assessment in Therapeutic Drug
Monitoring and Clinical Toxicology (KKGT), in close collaboration with the Ph.D
students R.J.M. Brüggemann (pharm D. UMCN ) and J.W. Alffenaar (pharm D. UMCG)
and dr. D.M. Burger of the
Radboud University Nijmegen Medical Centre and
prof. dr. D.R.A. Uges of the University Medical Center Groningen, the
Netherlands The
objectives of the program are to define sources of error in bioanalytical
methods, to contribute to the optimisation of the bioanalysis of antifungal
drugs and to establish interconvertibility of results among laboratories and
methods and comparison of interpretations and dosage recommendations. To see a (statistic) report example click here In
both rounds of 2008 there was a case included both measuring concentrations of
antifungals and a
clinical case. In
2012 In the first round of 2011 there was again a case included. Click to read the preface and the discussion of the patient case. For more information or participation you can download here all information about 2011 To download the form of the first round 2011 click right mousebutton and save as... To download the form of the second round 2011 click right mousebutton and save as... To download the the mailing sent with the samples click right mousebutton and save as... To see the concentrations of 2011 click right mousebutton and save as...
INTERNATIONAL QUALITY CONTROL PROGRAM FOR BIO-ANALYSIS OF TUBERCULOSIS DRUGS in
January 2012 a pilot study is started. This round is
organised in close collaboration with dr. J.W.C. Alffenaar and prof dr. D.R.A.
Uges of the University Medical Centre Groningen and dr. R.E. Aarnoutse of the
Radboud University Nijmegen Medical Centre. The objective of this program is to
define sources of error in bioanalytical methods, to contribute to optimisation
of bioanalysis of anti-tuberculosis drugs and to establish interconvertibility
of results among laboratories and methods. To download the form of the this pilot study click here
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U kunt een e-mailbericht met vragen of opmerkingen over deze website
verzenden aan
info@kkgt.nl.
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