KKGT  Stichting Kwaliteitsbewaking Klinische Geneesmiddelanalyse en Toxicologie

Start

Nieuws

English Version

Bestuur

Programma's

Controle serum

Concentraties testen

Uitslagformulieren

Verzendschema

Discussiedagen

Criteriumtabel

Hyperlinks

Jaarscore en Certificaat

 

Anti-HIV middelen 2010

 

1st round 2010

2nd round 2010

 

 test A (mg/l)

test B (mg/l)

test C
(mg/l)

 test A 
(mg/l)

test B
(mg/l)

test C
(mg/l)

Amprenavir

 8.62 0.602 4.29      

Atazanavir

 7.55 1.29 0.107 0.431 4.30 1.08

Darunavir

       4.45 1.11 6.66

Efavirenz

 0.426 12.16 3.64 0.102 1.02 9.72

Indinavir

 1.29 0.073 10.95 3.65 0.365 0.087

Lopinavir

 1.01 9.84 2.02 2.03 5.62 0.758

Nelfinavir

 4.46 7.42 8.89 0.743 0.742 3.71

Nevirapine

 10.02 3.50 2.00 1.00 15.00 3.75

Ritonavir

 2.03 0.728 6.06 4.05 1.46 4.04

Saquinavir

 0.282 0.282 1.25 5.02 1.88 0.338

Tipranavir

 17.92 29.82 35.72 59.68 14.90 89.39

 

Antischimmel Middelen 2010

 

1st round 2010

2nd round 2010

 

 test A (mg/l)

test B (mg/l)

 test A 
(mg/l)

test B
(mg/l)

Fluconazol

 7.91 19.80 3.98 23.74

Itraconazol

 0.398 4.26 0.300 5.68

OH-Itraconazol

 0.833 5.55 0.418 8.32

Voriconazol

 0.285 12.72 1.02 3.05

Posaconazol

 0.345 1.29 - 2.58

Flucytosine

 8.77 65.77 44.01 131.4

 

 

Toxicologie 2010

test A 

test B 

test C

test D
stof conc.(mg/l) stof conc (mg/l) stof conc.(mg/l) stof conc(mg/l)
salicylzuur 872 pentobarbital 33.19 ketamine 0.185* quetiapine 2.35
    paracetamol 76.73 ethanol 353* methadon 1.07
            ethanol 1115

*consensus waarden i.v.m. onverklaarbare resultaten.

 

Experimenteel 2010

test A

test B
stof conc. in µg/l stof conc in µg/l
A-1: cotinine ca. 125 venlafaxine 61,0
A-2: cotinine <10 desm.venlafaxine 256.5

test C

test D

stof

 conc. in µg/l stof conc in µg/l
sertraline 52.55 quetiapine 244.7
desm.sertraline 157.8    

 

Drugs of Abuse 2010

test A-1 

test A-2 
stof conc. in mg/l stof conc. in µg/l
ethanol 535 codeïne 1113
ranitidine 26,3 benzoylecgonine 622
    methylamfetamine 996
    oxazepam 1099

test B-1

test B-2
stof conc. in µg/l stof conc.in µg/l
flunitrazepam 286,2 fenfluramine 1535

test C-1

test C-2
stof conc. in µg/l stof conc. in µg/l
THCCOOH 60.2 codeïne 2035
methadon 3126

test D-1

test D-2
stof conc. in µg/l stof conc. in µg/l
codeïne 290 efedrine 1072
paracetamol 1069

 

Diversen  2010

test A

test B

test C
stof

conc in mg/l

 stof conc in mg/l

stof

 conc in µg/l
paracetamol 93.55 ethanol 951,2 atenolol 405
salicylzuur 253.8 methanol 595,8 metoprolol 310
ibuprofen 90.28 ethyleenglycol 948,5 propranolol 211
    trichloorethanol 108,4    

test D

 conc in µg/l
zuclopentixol 30.35
maprotiline 122.5
desm.maprotiline 155.4

 

Antiepileptica 

 eenheid test A test B test C test D
fenobarbital mg/l 23.76 9.58 57.46 28.76
fenytoïne mg/l 3.77 15.21 11.4 38.04
carbamazepine mg/l 4.89 2.46 7.39 14.79
10.11 –epoxide-CAZ mg/l 0.871 0.264 3.51 1.76
ethosuximide mg/l 44.27 19.19 133.8 66.99
valproïnezuur mg/l 18.96 84.97 212.3 42.51
monohydr.carbazepine mg/l 48.66 6.54 16.35 24.55
lamotrigine mg/l 30.73 12.40 0.743 6.20

 

Cardiaca

 eenheid test A test B test C test D
theofylline  mg/l 8.055 4.03 30.23 12.01
coffeïne  mg/l 8.717 4.36 13.96 34.65
flecaïnide mg/l 1.221 0.261 2.44 0.777
digoxine µg/l 0.718 0.448 3.74 1.61
amiodaron* mg/l 1.475 0.553 1.63 3.89
desethylamiodaron* mg/l 1.253 0.626 1.38 3.32

* consensuswaarden

 

Psychofarmaca I

 eenheid test A test B test C test D
amitriptyline µg/l 81.71 410.1 24.62 147.4
nortriptyline µg/l 150.2 314.1 25.14 90.30
clozapine µg/l 1605 644.4 174.1 463.2

Psychofarmaca  II

        
imipramine µg/l 89.9 26.92 359.1 161.4
desipramine µg/l 187.9 33.77 469.1 84.35
clomipramine µg/l 342.3 79.72 170.9 22.76
desm. clomipramine µg/l 359.0 134.4 75.29 32.23
lithium mmol/l 0.423 0.844 2.23 1.01

Psychofarmaca III

        
paroxetine µg/l 36.48 10.48 144.5 58.44
fluvoxamine µg/l 194.5 31.06 481.6 146.1
fluoxetine µg/l 316.4 52.63 940 422.5
desm. fluoxetine µg/l 173.3 69.16 686.3 347.0

Psychofarmaca IV

        
citalopram µg/l 106.8 23.08 136.6 383.9
desmethylcitalopram µg/l 34.23 9.13 45.07 91.18
risperidon µg/l 9.0 3.00 52.87 21.39
hydroxyrisperidon µg/l 32.28 8.61 106.2 53.72
olanzapine µg/l 160.5 13.77 40.76 68.72

 

Benzodiazepinen

 eenheid test A test B test C test D
diazepam µg/l 177.7 356.9 71.05 887.6
desm. diazepam µg/l 598.3 259.6 64.6 1435
temazepam µg/l 90.86 182.5 36.33 484.1
oxazepam µg/l 612.6 1077 76.55 3400
clonazepam µg/l 50.0 40.18 20 111
clobazam µg/l 137.4 394.3 58.88 784.6
desmethylclobazam µg/l 2492 3476 1384.2 6916

 

Antimicrobiële Middelen

 eenheid test A test B test C test D
gentamicine spiegel 1 mg/l 16.28 6.90 10.86 7.85
gentamicine spiegel 2 mg/l 3.97 0.979 9.93 3.97
tobramycine spiegel 1 mg/l 16.43 24.53 12.92 7.99
tobramycine spiegel 2 mg/l 7.99 5.00 2.01 2.99
vancomycine spiegel 1 mg/l 15.28 30.42 14.75 11.83
vancomycine spiegel 2 mg/l 11.83 13.82 9.93 5.91
amikacine spiegel 1 mg/l 3.00 2.02 4.52 5.96
amikacine spiegel 2 mg/l 20.79 10.41 13.97 34.6
methotrexaat spiegel 1 µmol/l 1.75 0.922 0.522 0.798
methotrexaat spiegel 2 µmol/l 65.02 2.61 17.26 32.47
 

terug naar boven

 

 

U kunt een e-mailbericht met vragen of opmerkingen over deze website verzenden aan info@kkgt.nl.