KKGT  Stichting Kwaliteitsbewaking Klinische Geneesmiddelanalyse en Toxicologie

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CRITERIA ANTI-HIV

mg/l

criteria, %

Amprenavir

0.2

20

Atazanavir

0.1 20

Darunavir

0.4 20

Efavirenz

0.2

20

Etravirine

0.05 30

Indinavir

0.1

20

Lopinavir

0.2

20

Nelfinavir

0.2

20

Nevirapine

0.2

20

Ritonavir

0.5

20

Raltegravir

0.02 30

Saquinavir

0.1

20

Tipranavir

0.8 20

Explanation:
the first column shows the drug to be analysed; the second column shows the lowest limit of quantitation the method of analysis of the participant has to meet and the third column shows the maximally allowed deviation from the theoretical value which is considered a ´good´ (OK) analytical result. Reported values outside the 80 – 120% area are considered as ´poor´ (not OK).

When the theoretical value is below the value in the second column the criteria for OK is 70-130%.
A certificate is obtained when at least 3 out of 4 results for each analyte are considered as ´good´.
For amprenavir, darunavir, etravirine, raltegravir and ribavirine both results must be OK.

Dr. D.J. Touw
Dr. D.M. Burger

for more information you can contact: info@kkgt.nl 

 

CRITERIA ANTIFUNGALS

mg/l criteria, %

Fluconazole

1.25 20

Itraconazole

0.125 20

Hydroxyitraconazole

0.125 20

Voriconazole

0.25 20

Posaconazole

0.125 20

Flucytosine

1.25 20

Explanation:
the first column shows the drug to be analysed; the second column shows the lowest limit of quantitation the method of analysis of the participant has to meet and the third column shows the maximally allowed deviation from the theoretical value which is considered a ´good´ (OK) analytical result. Reported values outside the 80 – 120% area are considered as ´poor´ (not OK).

When the theoretical value is below the value in the second column the criteria for OK is 70-130%.
A certificate is obtained when at least 3 out of 4 results for each analyte are considered as ´good´. 

KKGT office,

Dr. D.J. Touw

for more information you can contact: info@kkgt.nl 

 

 

 

 

 

 

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